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Caxton printed four-fifths of his works in English. He translated a large amount of works into English. He translated and edited a large amount of the work himself.

However, the English language was changing rapidly in Caxton's time and the works he was given to print were in a variety of styles and dialects. Caxton was a technician rather than a writer and he often faced dilemmas concerning language standardisation in the books he printed.

He wrote about this subject in the preface to his Eneydos. His successor Wynkyn de Worde faced similar problems.

Caxton is credited with standardising the English language homogenising regional dialects through printing. This was said to have led to the expansion of English vocabulary, the development of inflection and syntax and the ever-widening gap between the spoken and the written word.

However, Richard Pynson, who started printing in London in 1491 or 1492 and who favoured Chancery Standard, was a more accomplished stylist and consequently pushed the English language further toward standardisation.

It is asserted that the spelling ghost with the silent letter h was adopted by Caxton due to the influence of Dutch spelling habits.

Wynkyn de Worde (died 1534) was a printer and publisher known for his work with William Caxton, and is recognized as the first to popularize the products of the printing press.

De Worde was born in Woerth in Alsace; the name by which he is generally known means "Wynkyn of Woerth." Traditionally, he was believed to have accompanied Caxton to England in 1476; more recently, it has been argued that de Worde actually arrived c.1481, and that Caxton brought him to England to counter the competition of a second printer. (John Lettou set up a press in London in 1480.) De Worde improved the quality of Caxton's product; he was, in this view, "England's first typographer." In 1495, following Caxton's death in 1491 and a three-year litigation, de Worde took over Caxton's print shop.

De Worde is generally credited for moving English printing away from its late-Medieval beginnings and toward a modern model of functioning. Caxton had depended on noble patrons to sustain his enterprise; while de Worde enjoyed the support of patrons too (principally Margaret Beaufort, mother of King Henry VII), he shifted his emphasis to the creation of relatively inexpensive books for a commercial audience and the beginnings of a mass market. Where Caxton had used paper imported from the Low Countries, de Worde exploited the product of John Tate, the first English papermaker. De Worde published more than 400 books in over 800 editions (though some are extant only in single copies and many others are extremely rare). His greatest success, in terms of volume, was the Latin grammar of Robert Whittington, which he issued in 155 editions. Religious works dominated his output, in keeping with the tenor of the time; but de Worde also printed volumes ranging from romantic novels to poetry (he published the work of John Skelton and Stephen Hawes), and from children's books to volumes on household practice and animal husbandry. He innovated in the use of illustrations: while only about 20 of Caxton's editions contained woodcuts, 500 of de Worde's editions were illustrated.

He moved his firm from Caxton's location in Westminster to London; he was the first printer to set up a site on Fleet Street (1500), which for centuries became synonymous with printing. He was also the first man to build a book stall in St. Paul's Churchyard, which soon became a center of the book trade in London.

De Worde was the first to use italic type (1528) and Hebrew and Arabic characters (1524) in English books; and his 1495 version of Polychronicon by Ranulf Higdon was the first English work to use movable type to print music.